Skip to content
Toggle navigation
Toggle navigation
This project
Loading...
Sign in
SysBiOThe
/
CRA-Matlab
Go to a project
Toggle navigation
Toggle navigation pinning
Projects
Groups
Snippets
Help
Project
Activity
Repository
Pipelines
Graphs
Issues
0
Merge Requests
0
Wiki
Network
Create a new issue
Jobs
Commits
Issue Boards
Files
Commits
Network
Compare
Branches
Tags
Commit f7025376
authored
2019-03-31 21:53:54 +0200
by
Chiara Antonini
Browse Files
Options
Browse Files
Tag
Download
Email Patches
Plain Diff
Upload new file
1 parent
46a5ca2e
Hide whitespace changes
Inline
Side-by-side
Showing
1 changed file
with
76 additions
and
0 deletions
CRA_Updated_Version/CRA_Toolbox_bash/Examples/parameters_EGFR_IGF1R_model.m
CRA_Updated_Version/CRA_Toolbox_bash/Examples/parameters_EGFR_IGF1R_model.m
0 → 100644
View file @
f702537
% Model parameters
gamma_EGFR
=
0.02
;
gamma_IGF1R
=
0.02
;
kd_PIK3_active
=
0.005
;
k_p90Rsk_Erk
=
0.0213697
;
KM_p90Rsk_Erk
=
763523
;
k_SOS_EGFR
=
694.731
;
KM_SOS_EGFR
=
6086070
;
k_Ras_SOS
=
32.344
;
KM_Ras_SOS
=
35954.3
;
k_ERK_MEK
=
9.85367
;
KM_ERK_MEK
=
1007340
;
k_DSOS_p90Rsk
=
161197
;
KM_DSOS_p90Rsk
=
896896
;
k_SOS_IGF1R
=
500
;
KM_SOS_IGF1R
=
100000
;
k_PIK3_IGF1R
=
10.6737
;
KM_PIK3_IGF1R
=
184912
;
k_PIK3_EGFR
=
10.6737
;
KM_PIK3_EGFR
=
184912
;
k_Akt_PIK3
=
0.0566279
;
KM_Akt_PIK3
=
653951
;
kd_Akt
=
0.005
;
k_Erk_PP2A
=
9.85367
;
KM_Erk_PP2A
=
1007340
;
k_PIK3_Ras
=
0.0771067
;
KM_PIK3_Ras
=
272056
;
k_Raf_Ras
=
0.884096
;
KM_Raf_Ras
=
62464.6
;
k_Mek_Raf
=
185.759
;
KM_Mek_Raf
=
4768350
;
k_Raf_Akt
=
15.1212
;
KM_Raf_Akt
=
119355
;
k_Ras_RasGab
=
1509.36
;
KM_Ras_RasGab
=
1432410
;
k_MEK_PP2A
=
2.83243
;
KM_MEK_PP2A
=
518753
;
k_Raf_RafPP
=
0.126329
;
KM_Raf_RafPP
=
1061.71
;
kd_P90Rsk
=
0.005
;
% Input values
RafPP
=
120000
;
PP2A
=
120000
;
RasGapActive
=
120000
;
% Total concentrations
DSOS_tot
=
120000.0
;
Ras_tot
=
120000.0
;
Raf_tot
=
120000.0
;
Mek_tot
=
600000.0
;
Erk_tot
=
600000.0
;
p90Rsk_tot
=
120000.0
;
PIK3_tot
=
120000.0
;
Akt_tot
=
120000.0
;
% Initial conditions for state variables
EGFR_active_0
=
8000.0
;
IGF1R_active_0
=
650.0
;
SOS_0
=
0.0
;
Ras_active_0
=
0.0
;
Raf_active_0
=
0.0
;
Mek_active_0
=
0.0
;
Erk_active_0
=
0.0
;
p90Rsk_active_0
=
0.0
;
PIK3_active_0
=
0.0
;
Akt_active_0
=
0.0
;
Write
Preview
Styling with
Markdown
is supported
Attach a file
You are about to add
0
people
to the discussion. Proceed with caution.
Finish editing this message first!
Cancel
Please
register
or
sign in
to post a comment