compute_R0.m 1.2 KB
function R0=compute_R0(param)%,Tlock2,s02,s12)

be = param(1);
b0=param(2);
b1=param(3);
b2=param(4);
b3=param(5);
        
Norm=10^5; %882000
%Norm=882000;

be=be/(Norm);
b0=b0/(Norm);
b1=b1/(Norm);
b2=b2/(Norm);
b3=b3/(Norm);
        
FracSevere = param(6);
FracCritical = param(7);
FracMild = 1-FracSevere-FracCritical;
FracAsym = param(8);
               
IncubPeriod = param(9);
DurMildInf = param(10);

DurAsym = param(11);
   
DurHosp = param(12);
TimeICUDeath = param(13);
ProbDeath=param(14);

PresymPeriod=param(15)*IncubPeriod;
%PresymPeriod=param(15);
           
CFR=ProbDeath*FracCritical/100; 
            
a1=1/PresymPeriod; %presymptomatic period of transmission
a0=1/(IncubPeriod-PresymPeriod); %true latent period  

f=FracAsym;
    
g0=1/DurAsym;

g1=(1/DurMildInf)*FracMild;
p1=(1/DurMildInf)-g1;
    
p2=(1/DurHosp)*(FracCritical/(FracSevere+FracCritical));
g2=(1/DurHosp)-p2;
    
u=(1/TimeICUDeath)*(CFR/FracCritical);
    
g3=(1/TimeICUDeath)-u;


%s0 = (t<Tlock1) + s01 * (t>=Tlock1); %* (t<Tlock2) + s01(2)*(t>=Tlock2);
%s1 = (t<Tlock1) + s11 * (t>=Tlock1); %* (t<Tlock2) + s11(2)*(t>=Tlock2);

R0=Norm*(((be)/a1)+f*((b0)/g0)+(1-f)*(((b1)/(p1+g1))+(p1/(p1+g1))*(b2/(p2+g2)+ (p2/(p2+g2))*(b3/(u+g3)))));